COMPOSITION

  • Olmesartan Medoxomil 20 mg

PRODUCT DESCRIPTION

Cinque Terre

Introduction

Carolme 20 tablets contains Olmesartan medoxomil. It mainly reduces hypertension and antagonize the action of angiotensin II receptor.

 

Indication

  • Reduces hypertension
  • It also reduces the risk of fatal and nonfatal cardiovascular events
  • Cardiovascular risk management
  • Myocardial infraction

 

Dosage

Single dose once daily or as per patient condition

 

Mechanism of action

It produce its action by inhibiting the binding of angiotensin II to AT I. This causes AT I mediated vasoconstriction which causes decrease in the blood resistance and blood pressure.

 

Pharmacology

Absorption

The drug after oral administration is bioactivated by ester hydrolysis to olmesarton and which causes absorption from gastrointestinal tract.

Distribution

 The volume of distribution for the drug is about 17 ltrs. The drug is mainly bound to plasma protein and causes its penetration in red blood cells.

 

Excretion

The drug is mainly excreted through urine and feces.

 

 

Contraindication

  • Hypersensitivity to any of the ingredient

 

Precautions

  • In pregnant patients
  • Renal function impairment
  • Only to be used when prescribed

 


Cinque Terre