COMPOSITION

  • Telmisartan IP 40 mg

PRODUCT DESCRIPTION

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Introduction

Cartelma tablet contains Telmisartan . It is a drug mainly used in the management of hypertension by antagonizing the action of angiotensin II receptor.

 

Indications

  • Hypertension
  • Reduces the risk of cardiovascular events like strokes
  • Myocardial infarction
  • Arterial disease

 

Dosage

Once daily or as directed by the physician

 

 

Mechanism of action

The drug mechanism of action involves blocking the actions of angiotensin II receptor which effects vasoconstriction and aldosterone secreting effects which causes its effects on patient with high blood pressure.

 

 

Pharmacology

Absorption

After oral administration the peak concentration achieves within an hour. Presence of food effects the bioavailability of the drug.

 

 

Distribution

About 99.5% of the drug is bond to plasma protein. The volume of distribution of the drug is approximately 500 liters. Increased volume of distribution indicates more tissue binding.

Excretion

The drug is excreted in unchanged form in urine.

 

Contraindication

  • Not to be co-administered with anti-diabetic drug

 

Precautions

  • In pregnant patients
  • Can cause hypotension
  • Hyperkalemia
  • Impaired renal function

 


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