Suprova 5 tablet contains rosuvastatin . It belongs to the class of statins (HMG Co A reductase) which mainly use to treat high cholesterol.
- Helps in lowering bad cholesterol
- It increases high density lipoproteins ( good cholesterol)
- Slows atherosclerosis
- Reduces the risk of stroke
Mechanism of action
The drug produces its pharmacological action by inhibiting HMG Co A reductase enzyme. this enzyme mainly converts 3-hydroxy3methylglutaryl coenzyme A to mevalonate which is a precursor of cholesterol. It reduces the LDL and VLDL in body.
After oral administration of the drug attains peak plasma concentration in 3-5 hrs. Approximately the bioavailability of the drug 20%.
About 88% of the drug is bound to plasma protein. The mean volume of distribution of the drug is 134 liters.
About 90% of the drugs excreted in feces. The elimination of half concentration of the drug is 19 hrs.
- Hypersensitivity to any ingredient of the formulation
- Acute renal failure